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Biography
I am a bioinformatician who uses computational techniques to drive knowledge discovery in biology. I completed a M.Sc. in Computer Science with a focus on Bioinformatics at the University of Freiburg, Germany. In 2008, I commenced a Ph.D. at the University of Western Australia in which I developed novel methods for the computational prediction of non-coding RNA structure. In 2012, I joined CSIRO as a Postdoctoral Fellow to work on plant-pathogen interactions. In 2018, I joined the Australian National University as a Research Fellow at the Biological Data Science Institute and was awarded a 2019 ARC Discovery Early Career Researcher Award (DECRA) to uncover how rust fungi cause devastating plant diseases. In 2021 I joined CSIRO as a Senior Research Scientist where I lead the Data Intensive Approaches team.
I apply my analytical, collaborative and multi-disciplinary skills to a wide range of interesting biological problems. Some of my current research interests are:
- Interactions between plants and their pathogens with a focus on comparative genomics, evolution and infection mechanisms
- Application of machine learning to protein function prediction, such as effector prediction and subcellular localization prediction
- Achieving chromosome-scale assemblies of various species with long read sequencing and chromosome conformation capture data for spatial/temporal understanding of genome structure
- Function of small RNAs in host-pathogen interactions and relationships between molecule structure and function
I have released several widely used software tools for effector prediction using machine learning (http://effectorp.csiro.au/; http://apoplastp.csiro.au/), for plant and effector localization (http://localizer.csiro.au/) as well as for RNA structure prediction (http://dotknot.csse.uwa.edu.au/; http://knotseeker.csse.uwa.edu.au/). I am an accredited Software Carpentry instructor, I have taught Python in various short courses and I am passionate about reproducible and collaborative science.
Professional Areas
Current Roles
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Team Leader
Data Intensive Approaches
Academic Qualifications
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2012
Ph.D. in Bioinformatics
The University of Western Australia -
2007
Diplom (M. Sc.) in Computer Science
University of Freiburg
Professional Experiences
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2012-2018
Postdoctoral Fellow
CSIRO
Achievements and Awards
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2022-2026
Julius Career Award
CSIRO -
2021-2022
Thomas Davies Research Grant (AUD $20,000 offered to Early-and Mid-Career Researchers in the field of Marine, Soil and Plant Biology)
Australian Academy of Sciences -
2020-2020
ANU Pilot Project Award for single-cell sequencing of rust haustoria
10x Genomics -
2018-2018
Tansley Medal for excellence in Plant Science
New Phytologist -
2018-2018
INRA-CSIRO exchange scheme award
CSIRO -
2019-2022
Discovery Early Career Researcher Award 2019 (DE190100066, AUD $362,000)
Australian Research Council (ARC) -
2017-2017
Agriculture and Food Director’s Award in the category ‘Next-Generation Talent’
CSIRO -
2017-2017
Agriculture and Food Director’s Award in the category ‘Inclusion & Diversity’ (Team award)
CSIRO -
2009-2009
Google Australia and New Zealand Anita Borg Finalist
Google -
2008-2011
University Postgraduate Award for International Students (UPAIS)
The University of Western Australia -
2008-2011
International Postgraduate Research Scholarship (IPRS)
The University of Western Australia
Other highlights
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2021-2021
Invited keynote speaker: HiC workshop. Genomics Aotearoa. 18-19 February 2021, New Zealand.
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2020-2020
Invited keynote speaker: “From long-read sequencing to understanding genome biology: my journey in plant-pathogen interactions”. AMSI BioInfoSummer 2020, Australia.
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2020-2020
Invited keynote speaker: New Phytologist Next generation scientists 2020 meeting. University of Tartu, Estonia, postponed due to COVID-19
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2019-2019
Teacher for ‘Advanced Python’ in the ‘2nd Advanced Scientific Programming In Python - Asia Pacific’ course (Canberra, 20th-27th January 2019)
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2017-2017
Invited speaker: Queenstown Molecular Biology satellite meeting on “Plant-Microbe Interactions”. Queenstown Research Week, 3-6 September 2017, Queenstown, New Zealand.
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2016-2016
Invited speaker: IS-MPMI XVII Congress. Special session: Rust fungi – Molecular mechanisms underlying disease and resistance. 16-21 July 2016, Portland, United States.
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2014-2014
Invited speaker: Australian Pathogen Bioinformatics Symposium. 2 December 2014, The Australian National University, Canberra, Australia.
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2014-2014
Invited speaker: Pawsey Petascale Bioinformatics Symposium. 10 November, 2014, Perth, Australia.
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2013-2013
Invited speaker: EMBO workshop “Integrating omic approaches to host-pathogen interactions”. 25 – 28 June 2013, Liverpool, United Kingdom.
Publications
We have publications by Dr Jana Sperschneider